Fig. 1.

Screening for differential genes via TCGA database. (A) Screening for differential genes via the UALCAN online website. (B) The expression pattern of input genes with high expression in KIRC [the blue and red colors are log₂(TPM + 1) (TPM, transcripts per million)]. The bluer the color of the heatmap, the lower the gene expression, and the redder the color of the heatmap, the higher the gene expression. (C) Screening of 55 genes with up‐regulated expression and related to poor prognosis in ccRCC compared with normal tissue (we used the paired t‐test for statistical analysis, and P < 0.05 was considered statistically significant). (D) The expression pattern of input genes with low expression in KIRC, and the t‐test was used to determine the P values [the blue and red colors are log₂(TPM + 1)]. The bluer the color of the heatmap, the lower the gene expression, and the redder the color of the heatmap, the higher the gene expression). (E) Screening of 67 genes with down‐regulated expression and related to poor prognosis in ccRCC compared with normal tissue.