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. 2020 Dec 3;15(12):e0242861. doi: 10.1371/journal.pone.0242861

Table 2. Feasibility and acceptability of early infant screening for SCD.

Feasibility and acceptability variables Number of participants (N = 291) Percentage (%)
Mothers who accepted to be screened for Hb genotype 165 56.7
Children who were accepted to be screened for Hb genotype by mothers) 250 85.9
Reasons for wanting self/child to be screened*
Just to know my genotype and that of my child 231 91.7
Have a child with SCD 3 1.2
Had a child with SCD but late 0 0.0
My spouse and I are both carriers of SCD haemoglobin 3 1.2
The screening is free for me and my child 148 59.0
Other reason 7 3.8
Reasons for not wanting self/child to be screened*
I know my genotype 94 80
I know my child’s genotype 3 2.6
My husband and I are both AA 40 34.5
To avoid being worried 4 3.4
Don’t want my child to be pricked/bled 27 23.3
Will take time for the result to be ready 7 6.1
Do not like free test 3 2.7
Other reasons 8 9.1
Appropriate time a child should be screened for Hb
During pregnancy 38 13.0
Soon after birth 67 23.0
Within the first one-month of birth 105 36.1
Pre-school 43 14.8
Others 20 6.9
Don’t know 18 6.2
Willingness to enrol the child in SCD clinic immediately if SS/SC after testing 283 97.3
Willingness to pay ₦540.00(US$1·50) for rapid screening test 243 83.5
Affordability to pay ₦540.00(US$1·50) for rapid screening test 239 82.1
Willingness to pay ₦7,000.00 (US$20) for confirmatory Hb test) 190 65.3
Affordability to pay ₦7,00.00 (US$20) for confirmatory Hb test 143 49.1
Perceived challenges for early infant screening for Hb*
Cost of the confirmatory test at ₦7,000.00 (US$20) 190 65.3
Availability of test facility 155 53.3
Delay in getting the test result 149 51.2
Availability/accessibility for follow up care 148 50.9
Accessibility to test result 147 50.5
Time committed to counselling and testing 147 50.5
Cost of screening test at ₦540.00(US$1.50) 101 35.3
Fear of knowing the SCD status of the child 86 29.6
Other reasons 22 9.6

* multiple answers applied