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. 2020 Dec 3;15(12):e0242861. doi: 10.1371/journal.pone.0242861

Table 3. Validity and predictive accuracy of HemoTypeSC screening test.

Hb HemoTypeSC HPLC HemoTypeSC HemoTypeSC HemoTypeSC HemoTypeSC
Freq. (%) Freq. (%) Sensitivity Specificity PPV NPV
TP/(TP+FN) * TN/(FP+TN) * TP/(TP+FP) * TN/(TN+FN) *
AA 185 (74.0%) 185 (74.0%) 185/185 = 100% 65/65 = 100% 185/185 = 100% 65/65 = 100%
AS 53 (21.2%) 53 (21.2%) 53/53 = 100% 197/197 = 100% 52/52 = 100% 197/197 = 100%
AC 9(3.6%) 9 (3.6%) 9/9 = 100% 241/241 = 100% 9/9 = 100% 241/241 = 100%
SS 1 (0.4%) 1 (0.4%) 1/1 = 100% 249/249 = 100% 1/1 = 100% 249/249 = 100%
SC 1 (0.4%) 1 (0.4%) 1/1 = 100% 249/249 = 100% 1/1 = 100% 249/249 = 100%
CC 1 (0.4%) 1 (0.4%) 1/1 = 100% 249/249 = 100% 1/1 = 100% 249/249 = 100%

*TP (true positive); FN (false negative); TN (true negative); FP (false positive) PPV (positive predictive value); (NPV (negative predictive value)