Table 2. Rates of adverse pregnancy outcomes in subgroup of women in HAPO (adapted from data of McIntyre et al; Ref 4).
| Adverse Pregnancy Outcome | Missed GDM | Non-GDM | Excess Cases Missed | |||
|---|---|---|---|---|---|---|
| C/Tc | % | C/Tc | % | C | % | |
| Pregnancy-related hypertension | 23/242 | 9.5 | 709/4856 | 14.6 | -12.4 | -5.1 |
| Preterm | 18/253 | 7.1 | 264/4981 | 5.3 | 4.6 | 1.8 |
| Large-for-gestational age | 28/253 | 11.1 | 398/4975 | 8.0 | 7.8 | 3.1 |
| Primary Cesarean section | 33/216 | 15.3 | 758/4407 | 17.2 | -4.1 | -1.9 |
| Neonatal hyperinsulinemia | 27/229 | 11.8 | 311/4380 | 7.1 | 10.8 | 4.7 |
| Neonatal hypoglycemia | 33/194 | 17.0 | 634/3686 | 17.2 | 0.4 | -0.2 |
| Neonatal adiposity | 20/204 | 9.8 | 331/4037 | 8.2 | 3.3 | 1.6 |
C = Number of cases in the original publication.
Tc = calculated number of subjects having data, based on the percentage of patients reported to have the adverse outcome (the absolute number of cases not being reported in the publication; Tc = [Cx100]/%).
“Excess cases missed” is the difference in number of adverse outcomes associated with elevated glucose levels observed in women with a missed diagnosis of GDM compared with the expected rate of these complications, based on the rate observed in women not diagnosed with GDM (non-GDM).