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. 2020 Dec 3;15(12):e0243269. doi: 10.1371/journal.pone.0243269

Table 2. Use of hospital resources and outcomes.

Non-COVID-19 COVID-19 p-Value
n = 185 n = 212
Invasive support
Vasopressors–n (%) 84 (45.4) 108 (50.9) 0.317
Invasive mechanical ventilation–n (%) 26 (14.1) 105 (49.5) <0.001
Renal replacement therapy–n (%) 9 (4.9) 28 (13.2) 0.007
ECMO–n (%) 0 (0.0) 8 (3.8) 0.021
Transfusion–n (%) 24 (13.0) 35 (16.5) 0.397
Parenteral Nutrition–n (%) 5 (2.7) 13 (6.1) 0.163
Non-invasive positive pressure ventilation–n (%) 55 (29.7) 104 (49.1) <0.001
High flow nasal cannula–n (%) 12 (6.5) 99 (46.7) <0.001
Tracheostomy–n (%) 2 (1.1) 23 (10.8) <0.001
Outcomes
Duration of MV days–median [IQR] 4.00 [2.00–11.75] 9.00 [6.00–16.00] 0.003
NIV failure–n (%) 4 (2.2) 43 (20.3) <0.001
28-day all-cause mortality–n (%) 27 (14.6) 19 (9.0) 0.066
60-day all-cause mortality–n (%) * 32 (17.3) 23 (10.8) 0.087
28-day mortality in ventilated patients–n (%) * 9/26 (34.6%) 17/105 (16.2%) 0.114
ICU LOS–days median [IQR] 3.00 [2.00–4.00] 7.00 [2.00–15.00] <0.001
Hospital LOS–days median [IQR] 12.00 [7.00–24.00] 17.50 [11.00–31.00] <0.001

*Three patients were excluded because they were still in patients with a follow-up shorter than 60 days.