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. 2020 Dec 3;15(12):e0243268. doi: 10.1371/journal.pone.0243268

Table 1. Patient demographic characteristics according to period between initial symptoms and clinical progression to COVID-19 suspicion (PISYCS).

Period between initial symptoms and clinical progression to COVID-19 suspicion (PISYCS) Global P Value
<24 Hrs (n = 9759) 1–3 Days (n = 28331) 4–7 Days (n = 20877) >7 Days (n = 6533)
N % N % N % N %
Gender Female 4686 14.3%* 14371 43.7% 10562 32.1% 3260 9.9% <0.001
Male 5073 15.6% 13960 42.8% 10315 31.6% 3273 10.0%
Age < 30 2469 15.0%* 7965 48.4% 4732 28.7%** 1302 7.9%*** <0.001
30–49 3745 12.8% 12813 43.6% 9785 33.3% 3016 10.3%
50–59 1430 14.7% 3875 39.7% 3321 34.1% 1123 11.5%
60–69 1095 19.8% 2006 36.2% 1785 32.2% 656 11.8%
70–79 615 21.9% 1018 36.3% 863 30.7% 311 11.1%
> 80 405 25.7% 654 41.5% 391 24.8% 125 7.9%
Mean (SD) 43(20)* 40 (18) 42 (17)** 44 (16)*** <0.001
State’s Socioeconomic Status High 5532 15.1%* 15745 43.1% 11352 31.1%** 3921 10.7%*** <0.001
Medium 2878 15.8% 8027 44.2% 5868 32.3% 1402 7.7%
Low 1349 12.5% 4559 42.3% 3657 33.9% 1210 11.2%
Health Sector Private 468 15.6%* 1228 40.9% 885 29.5%** 418 13.9%*** <0.001
With SS 4584 18.6% 10515 42.6% 7274 29.5% 2321 9.4%
Without SS 4707 12.5% 16588 43.9% 12718 33.6% 3794 10.0%
Indigenous Language Speaker Yes 98 14.4% 277 40.8% 242 35.6% 62 9.1% 0.20
No 9661 14.9% 28054 43.4% 20635 31.8% 6471 10.0%
Pregnancy Yes 139 18.3% 383 50.5% 190 25.1%** 46 6.1%*** <0.001
No 9620 14.9% 27948 43.2% 20687 32.0% 6487 10.0%
Tobacco Use Yes 946 14.5% 2786 42.8% 2122 32.6% 661 10.1% 0.49
No 8813 14.9% 25545 43.3% 18755 31.8% 5872 10.0%
Diabetes Yes 1514 18.1%* 3307 39.5% 2684 32.1%** 867 10.4%*** <0.001
No 8245 14.4% 25024 43.8% 18193 31.8% 5666 9.9%
COPD Yes 401 22.6%* 685 38.6% 535 30.2% 153 8.6% <0.001
No 9358 14.7% 27646 43.4% 20342 31.9% 6380 10.0%
Asthma Yes 394 12.4%* 1422 44.6% 1034 32.5% 336 10.5% 0.001
No 9365 15.0% 26909 43.2% 19843 31.8% 6197 9.9%
Immunosuppression Yes 455 26.1%* 697 40.0% 429 24.6%** 163 9.3% <0.001
No 9304 14.6% 27634 43.3% 20448 32.1% 6370 10.0%
Hypertension Yes 1932 17.4%* 4415 39.7% 3593 32.3%** 1194 10.7%*** <0.001
No 7827 14.4% 23916 44.0% 17284 31.8% 5339 9.8%
Cardiovascular Disease Yes 470 22.0%* 820 38.3% 627 29.3% 224 10.5%*** <0.001
No 9289 14.7% 27511 43.4% 20250 32.0% 6309 10.0%
Obesity Yes 1381 13.5% 4093 40.0% 3633 35.5%** 1119 10.9%*** <0.001
No 8378 15.2% 24238 43.9% 17244 31.2% 5414 9.8%
Chronic Kidney Disease Yes 435 28.1%* 612 39.5% 374 24.1%** 129 8.3% <0.001
No 9324 14.6% 27719 43.3% 20503 32.1% 6404 10.0%
Other Comorbid Condition Yes 662 19.0%* 1440 41.3% 1059 30.4% 323 9.3% <0.001
No 9097 14.7% 26891 43.4% 19818 32.0% 6210 10.0%

SS = Social Security. COPD = Chronic Obstructive Pulmonary Disease. SD = Standard Deviation. Statistical Significance p<0.05

* Significant Difference between periods of <24 hrs. and 1–3 days

** Significant Difference between periods of 4–7 days and 1–3 days.

*** Significant Difference between periods of >7 days and 1–3 days.