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. 2020 Dec 3;15(12):e0243268. doi: 10.1371/journal.pone.0243268

Table 2. Medical decisions according period between initial symptoms and clinical progression to COVID-19 suspicion (PISYCS).

Period between initial symptoms and clinical progression to COVID-19 suspicion (PISYCS)PISYCS Global P Value
<24 Hrs (n = 9759) 1–3 Days (n = 28331) 4–7 Days (n = 20877) >7 Days (n = 6533)
N % N % N % N %
Type of care Ambulatory Care 5547 56.8%* 22742 80.3% 15674 75.1%** 4837 74.0%*** <0.001
Hospital Admission 4212 43.2% 5589 19.7% 5203 24.9% 1696 26.0%
Admission to the ICU 271 2.8%* 503 1.8% 563 2.7%** 208 3.2%*** <0.001
Mechanical Ventilation 155 1.6% 479 1.7% 525 2.5%** 189 2.9%*** <0.001
Result of RT-PCR Test+ Not Positive to SARS-CoV 2 7036 81.4%* 19801 80.4% 12672 69.8%** 3910 66.5%*** <0.001
Positive to SARS-CoV-2 1601 18.6% 4818 19.6% 5462 30.2% 1961 33.5%

ICU = Intensive Care Unit. PCR = Polymerase Chain Reaction. SD = Standard Deviation.

Statistical Significance p<0.05

*Significant Difference between periods of <24 hrs and 1–3 days.

** Significant Difference between periods of 4–7 days and 1–3 days.

*** Significant Difference between periods of >7 days and 1–3 days. + Undefined were not included.