Table 7. Three SNPs identified with tissue specific gene expression of their associated genes and /or eQTLs, using the Genotype-Tissue Expression (GTEx) database (http://gtexportal.org).

SNP	Gene	Tissue	NES
rs12587898	IFI27L1	Brain cortex	0.41
rs1179161	PNPLA4	Tibial nerve	0.42
“	“	Frontal cortex	0.21
“	“	Putamen	0.25
“	“	Spinal cord	0.36
“	“	Cortex	-0.39
“	“	Caudate	0.18
rs645026	YEATS4	Caudate	-0.45

The normalized effect size (NES) defined as the slope of the linear regression of the effect of the alternative (minor) allele relative to the reference (major) allele, based on hg19 reference genome [34].