Table 11. Results for dependencies adjusted for the confounding effect of ethnicity.
A. is for the Bayley phenotypes, and B is for the growth phenotypes.
| A | |||||||||
| Bayley Phenotype | SNP | Gene | MI | P-value (MI) | FWER (MI) | Adjusted MI | P-value (Adj.) | p-value change (%) | FWER (Adj.) |
| Motor | rs10833478 | NELL1 | 0.0843 | 3.41E-07 | 0.142 | 0.0846 | 3.25E-07 | 4.7% | 0.135 |
| Motor | rs645026 | YEATS4 | 0.0832 | 4.40E-07 | 0.180 | 0.0828 | 4.78E-07 | 8.7% | 0.197 |
| Adaptive | rs7387693 | MTMR7 | 0.0847 | 9.54E-07 | 0.359 | 0.0844 | 1.05E-06 | 9.9% | 0.384 |
| Adaptive | rs7462219 | MTMR7 | 0.0807 | 2.67E-06 | 0.693 | 0.0802 | 2.96E-06 | 11.1% | 0.735 |
| Adaptive | rs4955988 | CACNA2D3 | 0.0817 | 2.13E-06 | 0.617 | 0.0812 | 2.38E-06 | 11.5% | 0.651 |
| Adaptive | rs1291359 | HTR7P1 | 0.0829 | 1.55E-06 | 0.506 | 0.0839 | 1.17E-06 | 24.2% | 0.414 |
| Language | rs11658800 | ELAC2 | 0.0803 | 2.48E-06 | 0.670 | 0.0828 | 1.31E-06 | 46.9% | 0.437 |
| Language | rs7239403 | SMIM21 | 0.0803 | 2.51E-06 | 0.675 | 0.0853 | 7.42E-07 | 70.5% | 0.288 |
| Social-Emotional | rs12434723 | C14orf177 | 0.0805 | 2.61E-06 | 0.680 | 0.0858 | 7.26E-07 | 72.2% | 0.272 |
| Social-Emotional | rs11628108 | C14orf177 | 0.0826 | 1.56E-06 | 0.510 | 0.0881 | 3.59E-07 | 77.0% | 0.143 |
| Motor | rs7155811 | TMEM260 | 0.0772 | 2.16E-06 | 0.610 | 0.0940 | 5.45E-08 | 97.5% | 0.020 |
| Social-Emotional | rs1161106 | LOC100507175 | 0.0811 | 2.28E-06 | 0.634 | 0.0780 | 4.78E-06 | 109.2% | 0.876 |
| Motor | rs1449848 | CPNE8 | 0.0772 | 2.16E-06 | 0.607 | 0.0645 | 5.19E-05 | 2305.1% | 1.000 |
| B | |||||||||
| Growth Phenotype | SNP | Gene | MI | P-value (MI) | FWER (MI) | Adjusted MI | P-value (Adj. MI) | p-value change (%) | FWER (Adj.) |
| Linf | rs12734338 | PPP1R12B | 0.1130 | 2.23E-09 | 0 | 0.1141 | 2.23E-09 | 0.0% | 0 |
| Linf | rs7981995 | DACH1 | 0.0232 | 7.18E-06 | 0.936 | 0.0231 | 7.57E-06 | 5.5% | 0.944 |
| Alpha | rs7101173 | MIR6072 | 0.0248 | 2.54E-06 | 0.619 | 0.0247 | 2.71E-06 | 6.7% | 0.643 |
| Linf | rs373680 | FBXO33 | 0.0232 | 6.94E-06 | 0.93 | 0.0235 | 5.83E-06 | 16.0% | 0.895 |
| Lambda | rs4793500 | CASC17 | 0.0259 | 1.16E-06 | 0.358 | 0.0256 | 1.46E-06 | 25.5% | 0.427 |
| Lambda | rs564266 | NTM | 0.0241 | 4.05E-06 | 0.771 | 0.0249 | 2.47E-06 | 39.0% | 0.620 |
| Lambda | rs773024 | OSTF1 | 0.0236 | 5.53E-06 | 0.855 | 0.0229 | 8.57E-06 | 55.0% | 0.952 |
| Linf | rs6884117 | C5orf22 | 0.0241 | 3.86E-06 | 0.761 | 0.0234 | 6.18E-06 | 60.1% | 0.908 |
| Lambda | rs154444 | ZNF608 | 0.0232 | 7.08E-06 | 0.916 | 0.0257 | 1.33E-06 | 81.2% | 0.404 |
| Linf | rs7071157 | PFKFB3 | 0.0276 | 4.08E-07 | 0.157 | 0.0300 | 7.13E-08 | 82.5% | 0.031 |
| Linf | rs6570627 | UTRN | 0.0250 | 2.20E-06 | 0.576 | 0.0240 | 4.19E-06 | 90.1% | 0.789 |
| Alpha | rs10196354 | ERBB4 | 0.0232 | 7.23E-06 | 0.937 | 0.0284 | 2.14E-07 | 97.0% | 0.085 |
| Lambda | rs6672510 | PDL5 | 0.0316 | 3.12E-08 | 0.013 | 0.0298 | 9.81E-08 | 214.3% | 0.038 |
| Alpha | rs9691259 | IGFBP3 | 0.0258 | 1.30E-06 | 0.4 | 0.0232 | 7.40E-06 | 469.8% | 0.937 |
| Linf | rs6710428 | CERS6 | 0.0264 | 8.83E-07 | 0.301 | 0.0224 | 1.19E-05 | 1253.3% | 0.993 |
| Lambda | rs7075547 | LRRTM3 | 0.0237 | 5.15E-06 | 0.836 | 0.0043 | 4.07E-01 | 7893823% | 1 |
We show the population wide mutual informations and corresponding p-values, with the adjusted mutual informations and p-values, followed by the FWER value. The three sets of SNP-phenotypes separated by thick lines are those for which: upper–the absolute change in p-values is less than 25% of the original; middle–the change in p-value is less than 100%; lower the change in p-value is greater than 100%. Note that there are some dependencies for which the p-values improve on adjustment for ethnicity confounding.