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. 2020 Dec 3;15(12):e0243102. doi: 10.1371/journal.pone.0243102

Table 2. Characteristics of 662 persons initiating isoniazid treatment for latent tuberculosis infection.

95% Confidence Interval
n % or Mean of Total Lower Upper
Pre-Treatment Testing Pattern
    One TST 339 51.21% 47.39% 55.01%
    One IGRA 191 28.85% 25.52% 32.43%
    One TST followed by one IGRA 58 8.76% 6.83% 11.17%
    Other pattern of multiple TSTs and/or IGRAs 74 11.18% 8.99% 13.82%
Sex
    Female 358 54.08% 50.26% 57.85%
    Male 304 45.92% 42.15% 49.74%
Age Group
    0–14 88 13.29% 10.91% 16.11%
    15–29 182 27.49% 24.22% 31.03%
    30–44 184 27.79% 24.51% 31.34%
    45–64 208 31.42% 27.99% 35.07%
Census Region
    Northeast 210 31.72% 28.28% 35.38%
    Midwest 101 15.26% 12.71% 18.21%
    South 94 14.20% 11.74% 17.08%
    West 257 38.82% 35.17% 42.60%
Patient Location
    Large Central Metro County (Urban) 313 47.28% 43.49% 51.10%
    Large Fringe Metro County (Suburban) 253 38.22% 34.58% 41.99%
    Any Smaller County 96 14.50% 12.01% 17.40%
% of Households Under FPL in County
    <15% 374 56.50% 52.68% 60.24%
    ≥15% 288 43.50% 39.76% 47.32%
Insurance Type
    HMO 98 14.80% 12.29% 17.73%
    POS 473 71.45% 67.88% 74.77%
    PPO 91 13.75% 11.32% 16.59%
Supply of Isoniazid Received on Date of 1st Fill
    < 2 month supply 611 92.30% 90.00% 94.10%
    ≥2 month supply 51 7.70% 5.90% 10.00%
Period Regimen Started
    2011 Q3-4 142 21.45% 18.48% 24.75%
    2012 Q1-4 261 39.43% 35.76% 43.21%
    2013 Q1-4 227 34.29% 30.76% 38.00%
    2014 Q1 32 4.83% 3.44% 6.76%
State TB Rate/100,000 - 3.89 3.78 4.00
% Foreign Born in County - 20.95 20.00 21.91
Count of Clinical Risk Factors*
    None 407 61.48% 57.70% 65.12%
    1 192 29.00% 25.66% 32.59%
    2 or more 63 9.52% 7.50% 12.01%

* Clinical risk factors included diabetes, tobacco use, a history or late effects of TB, contact with or exposure to TB, HIV, and immune-suppressive medication use.

Abbreviations

HIV: Human immunodeficiency virus

HMO: Health maintenance organization

IGRA: Interferon gamma release assay

POS: Place of service

PPO: Preferred provider organization

Q1: Quarter 1 of the calendar year

Q1-4: Quarters 1–4 of the calendar year (full year)

Q3-4: Quarters 3 and 4 of the calendar year

TB: Tuberculosis

TST: Tuberculin skin test