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No effect of ALY688 (100, 300, and 500 nM) on basal (Bas) and insulin (Ins, 100 nM)-stimulated glucose uptake in epididymal (Epid, A) and subcutaneous inguinal (Sc Ing, B) adipocytes. Glucose uptake was also assessed in Epid adipocytes exposed to 500 nM of ALY688 for 60 min (c) and then stimulated with 10 and 100 nM of insulin. Different letters denote statistical significance (p < 0.05). Two-way ANOVA, n = 3–5
