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. 2020 Nov 23;12(1):1842990. doi: 10.1080/19490976.2020.1842990

Figure 1.

Figure 1.

Phlorizin (PHZ) attenuated high-fat diet (HFD)-induced obesity. (a) Changes in the body weight of mice over 12 weeks. At week 12, multiple obesity-related parameters were recorded for the four groups of mice receiving normal chow diet (NCD), NCD with PHZ (NCD+PHZ), HFD, and HFD with PHZ (HFD+PHZ), respectively. The parameters included: (b) food intake; (c) energy intake; (d) fat mass; (e) weights of different organs; morphological observations of the (f) liver and (g) epididymis fat; (h) hematoxylin and eosin staining of epididymis fat; (i) adipocyte size of epididymis fat; levels of serum (j) lipopolysaccharide (LPS) and (k) glucagon-like peptide-1 (GLP-1); (l) fasting blood insulin; (m) fasting glucose; (n) homeostasis model assessment (HOMA)-insulin resistance (IR) index; (o) HOMA-insulin sensitivity (IS) index; (p) oral glucose tolerance test; (q) insulin tolerance test. Data are expressed as mean ± standard deviation. One-way ANOVA was used to analyze statistical differences; NS for P > .05, *P < .05, **P < .01, and ***P < .001