Table 2.
Correlations between key gut microbial taxa and metabolites [short-chain fatty acids (SCFAs) and lipopolysaccharide (LPS)]
| Taxa | Acetic acid |
Propionic Acid |
Isobutyric Acid |
Butyrate acid |
Isovaleric acid |
Valerate Acid |
Total SCFAs |
Blood LPS |
Fecal LPS |
|---|---|---|---|---|---|---|---|---|---|
| Eubacterium oxidoreducens group | −.593 | −.534 | −.417 | −.591 | −.349 | −.272 | −.629 | .557 | .631 |
| Ruminococcaceae NK4A214 group | −.405 | −.457 | −.277 | −.363 | −.119 | −.182 | −.439 | .332 | .531 |
| Lachnospiraceae FCS020 group | −.430 | −.374 | −.350 | −.418 | −.289 | −.121 | −.458 | .278 | .551 |
| Christensenellaceae R-7 group | −.506 | −.466 | −.420 | −.539 | −.298 | −.297 | −.550 | .249 | .409 |
| Rikenellaceae RC9 gut group | −.486 | −.387 | −.359 | −.480 | −.282 | −.202 | −.504 | .428 | .592 |
| Ruminococcaceae UCG-004 | .036 | −.005 | .019 | .101 | −.129 | −.042 | .035 | −.160 | .074 |
| Ruminococcaceae UCG-003 | −.554 | −.462 | −.088 | −.509 | −.122 | −.266 | −.565 | .454 | .610 |
| Ruminococcaceae UCG-009 | −.693 | −.591 | −.090 | −.620 | −.136 | −.336 | −.702 | .544 | .758 |
| Lachnospiraceae UCG-004 | −.411 | −.419 | −.355 | −.397 | −.403 | −.258 | −.453 | .418 | .444 |
| Lachnospiraceae UCG-008 | −.557 | −.533 | −.345 | −.556 | −.355 | −.318 | −.602 | .474 | .576 |
| Lachnospiraceae UCG-006 | −.689 | −.577 | −.248 | −.665 | −.439 | −.290 | −.713 | .584 | .763 |
| Phascolarctobacterium | −.091 | −.136 | −.291 | −.244 | −.203 | .119 | −.137 | .027 | .002 |
| Erysipelatoclostridium | −.470 | −.301 | −.327 | −.486 | −.310 | −.099 | −.479 | .360 | .514 |
| NS3a marine group | .019 | −.053 | −.091 | .155 | .156 | .133 | .029 | −.196 | −.119 |
| Ruminiclostridium 5 | −.606 | −.508 | −.015 | −.563 | −.137 | −.309 | −.614 | .495 | .651 |
| Ruminiclostridium 9 | −.721 | −.623 | −.233 | −.687 | −.332 | −.298 | −.747 | .618 | .815 |
| Lachnoclostridium | −.614 | −.609 | −.232 | −.568 | −.334 | −.424 | −.655 | .484 | .636 |
| Ruminococcus 1 | −.040 | −.060 | −.049 | −.028 | −.238 | −.106 | −.062 | .012 | .211 |
| GCA-900066575 | −.568 | −.376 | −.028 | −.555 | −.103 | −.205 | −.556 | .564 | .714 |
| Anaerotruncus | −.623 | −.518 | −.050 | −.560 | −.094 | −.304 | −.627 | .498 | .657 |
| Oscillibacter | −.470 | −.416 | −.311 | −.458 | −.404 | −.165 | −.503 | .421 | .518 |
| Acetatifactor | −.515 | −.429 | .091 | −.471 | .034 | −.194 | −.513 | .382 | .567 |
| Harryflintia | −.683 | −.617 | −.162 | −.635 | −0.28 | −.308 | −.708 | .594 | .733 |
| Tyzzerella 3 | .467 | .375 | .123 | .381 | −.017 | .048 | .464 | .110 | −.238 |
| ASF356 | .552 | .262 | .018 | .485 | −.043 | −.139 | .507 | −.229 | −.438 |
| Roseburia | −.158 | −.366 | −.306 | −.142 | −.269 | .022 | −.220 | .039 | .222 |
| Blautia | −.131 | −.208 | −.094 | −.214 | −.167 | .004 | −.176 | .072 | .129 |
| Alistipes | −.040 | −.013 | .192 | −.034 | .058 | .315 | −.022 | .162 | −.081 |
| Desulfovibrio | −.541 | −.331 | .066 | −.431 | −.022 | −.265 | −.509 | .401 | .413 |
| Helicobacter | −.462 | −.428 | −.315 | −.419 | −.369 | −.242 | −.492 | .407 | .459 |
| Bilophila | −.492 | −.395 | .098 | −.439 | .060 | −.215 | −.485 | .366 | .534 |
| Verruc-01 | −.492 | −.423 | −.397 | −.490 | −.278 | −.155 | −.518 | .421 | .453 |
| Mucispirillum | −.507 | −.421 | .065 | −.447 | −.014 | −.247 | −.505 | .376 | .507 |
| A2 | −.709 | −.590 | −.367 | −.666 | −.296 | −.322 | −.731 | .582 | .727 |
Statistically significant Pearson correlations are in boldface type.