Table 3.
Studies comparing different PD-L1 IHC assays
|
# and types of tested tumors |
SP142 |
SP263 |
28–8 |
22C3 |
E1L3N |
Ref |
Hirsch et al. | 39 NSCLC | - | + | + | + | NE | 26 |
Karim et al. | 29 NSCLC | + | NE | + | + | 27 | |
Scognamiglio et Chen | 96 HNSCC | + | +++ | NE | NE | + | 21 |
Rimm et al. | 90 NSCLC | - | NE | + | + | NE | 28 |
Abbreviations: #, number; HNSCC, head and neck squamous cell carcinoma; NE, not evaluated; NSCLC, non–small-cell lung cancer.
SP142 (Spring Bioscience), SP263 (Ventana), 28–8 (Dako), 22C3 (Dako) and E1L3N (Cell Signaling)