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Silencing of SNHG1 inhibits the osteogenic differentiation of LFCs. A-B, mRNA (a) and protein (b) expression of osteogenesis-related factors BMP-2, RUNX2 and OCN determined by QRT-PCR and western blot analysis, respectively; C-D, the osteogenic properties of LFCs determined by alizarin red staining (c) and ALP (d) staining. The data are expressed as the mean ± SD. Two-way ANOVA and Tukey’s multiple comparison test was used to determine statistical significance; *, p < 0.05
