Figure 7.

IGF2BP2 knockdown combined with FBXL19-AS1 knockdown increased the effect of DOX in promoting apoptosis of U87 cells

(A) Alone or combination use of IGF2BP2 knockdown and FBXL19-AS1 knockdown increased the promotional effect of DOX on the apoptosis rate of U87 cells. Results were analysed using one-way ANOVA test. Data represent mean ± SD (n = 3, each). *P < 0.05 vs. Control group, ^#P < 0.05 vs. DOX group, ^&&P < 0.01 vs. DOX+IGF2BP2 (-) group, ^▲▲P < 0.05 vs. DOX+FBXL19-AS1 (-) group. (B) The schematic diagram about the regulation process of IGF2BP2/FBXL19-AS1/ZNF765 axis on BTB permeability.