Figure 2.

GQD-CRC ingredient-target pharmacology network. Ellipses represent the BCIs of GQD. BCIs of Gancao, Gegen, Huangqin, and Huanglian are painted in green, brown, purple, and yellow, respectively. Shared BCIs of multiple medicines are painted in red. V-shaped polygons in blue represent the target genes of BCIs. The regulation relationships between BCIs and their targets are displayed as lines in figure. Abbreviations: BCI, bioactive chemical ingredient; GQD, Gegen Qinlian decoction; CRC, colorectal cancer.