Table 3.
Information of 20 target genes in the pharmacological network.
| Gene | Full name | Log2FC | Adjusted P value | Aliases |
|---|---|---|---|---|
| PTGS2 | Prostaglandin G/H synthase 2 | 1.7769 | 7.39E − 03 | PGHS-2; COX-2; PHS-2; PGG/HS; hCox-2; GRIPGHS |
| OLR1 | Oxidized low-density lipoprotein receptor 1 | 1.9948 | 4.17E − 03 | LOX1; LOXIN; SLOX1; CLEC8A; SCARE1 |
| NR3C2 | Nuclear receptor subfamily 3 group C member 2 | −1.5129 | 3.92E − 03 | MR; MCR; MLR; NR3C2VIT |
| HSD3B2 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 | −1.1592 | 8.47E − 03 | HSDB; HSD3B; SDR11E2 |
| TNFSF15 | TNF superfamily member 15 | 1.0461 | 1.24E − 02 | TL1; TL1A; VEGI; TNLG1B; VEGI192A |
| MMP1 | Matrix metallopeptidase 1 | 3.2300 | 2.86E − 03 | CLG; CLGN |
| AKR1C3 | Aldo-keto reductase family 1 member C3 | −1.2267 | 6.79E − 03 | DD3; DDX; PGFS; HAKRB; HAKRe; HA1753; HSD17B5; hluPGFS |
| CA2 | Carbonic anhydrase 2 | −1.7184 | 9.85E − 03 | CAC; CAII; Car2; CAII; HEL-76; HEL-S-282 |
| MMP3 | Matrix metallopeptidase 3 | 4.1101 | 1.41E − 03 | SL-1; STMY; STR1; CHDS6; MMP3; STMY1 |
| PLAU | Plasminogen activator, urokinase | 1.2642 | 4.83E − 03 | ATF; QPD; UPA; URK; u-PA; BDPLT5 |
| MMP9 | Matrix metallopeptidase 9 | 1.1245 | 8.08E − 03 | GELB; CLG4B; MMP9; MANDP2 |
| IL1B | Interleukin 1 beta | 2.1239 | 2.27E − 03 | IL-1; IL1F2; IL1beta; IL1-BETA |
| DUOX2 | Dual oxidase 2 | 1.9328 | 2.98E − 02 | TDH6; LNOX2; THOX2; NOXEF2; P138-TOX |
| CCNB1 | Cyclin B1 | 1.0204 | 1.50E − 02 | CCNB |
| ABCG2 | ATP binding cassette subfamily G member 2 | −2.9521 | 2.92E − 03 | MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; GOUT1; MXR-1; CDw338; UAQTL1; EST157481 |
| CXCL11 | C-X-C motif chemokine ligand 11 | 3.4122 | 2.12E − 03 | IP9; H174; IP-9; b-R1; I-TAC; SCYB11; SCYB9B |
| CXCL10 | C-X-C motif chemokine ligand 10 | 2.1322 | 6.06E − 03 | C7; IFI10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10 |
| SPP1 | Secreted phosphoprotein 1 | 1.5076 | 7.22E − 03 | OPN; BNSP; BSPI; ETA-1 |
| ADH1C | Alcohol dehydrogenase 1C (class I), gamma polypeptide | −2.9047 | 7.54E − 03 | ADH3 |
| MAOA | Monoamine oxidase A | −1.1045 | 7.88E − 03 | BRNRS; MAO-a |
FC, fold change.