Table 1.
Correlation between IL-18 expression and clinicopathological features in patients with colon cancer (n = 116).
| Variable | n | IL-18 expression | P value∗ | ||
|---|---|---|---|---|---|
| Negative (76) | Weak (23) | Strong (17) | |||
| Age | 0.668 | ||||
| <60 | 54 | 36 | 9 | 9 | |
| ≥60 | 62 | 40 | 14 | 8 | |
| Gender | 0.826 | ||||
| Male | 68 | 46 | 13 | 9 | |
| Female | 48 | 30 | 10 | 8 | |
| Location | 0.603 | ||||
| Right | 58 | 38 | 13 | 7 | |
| Transverse | 29 | 17 | 7 | 5 | |
| Left | 29 | 21 | 3 | 5 | |
| T stage | 0.001∗ | ||||
| T1+T2 | 63 | 33 | 20 | 10 | |
| T3+T4 | 53 | 43 | 3 | 7 | |
| N stage | 0.191 | ||||
| N0 | 64 | 46 | 9 | 9 | |
| N1+N2 | 52 | 30 | 14 | 8 | |
| M stage | 0.585 | ||||
| M0 | 114 | 74 | 23 | 17 | |
| M1 | 2 | 2 | 0 | 0 | |
| AJCC stage | 0.013∗ | ||||
| I | 45 | 22 | 11 | 12 | |
| II | 22 | 12 | 7 | 3 | |
| III | 37 | 31 | 4 | 2 | |
| IV | 13 | 11 | 1 | 1 | |
| Differentiation | 0.407 | ||||
| Well | 39 | 26 | 7 | 6 | |
| Moderate | 58 | 35 | 15 | 8 | |
| Poor | 19 | 15 | 1 | 3 | |
∗ P values are based on chi-squared or Fisher's exact test. P < 0.05 indicates a significant association among the variables.