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. 2020 Dec 4;63:103154. doi: 10.1016/j.ebiom.2020.103154

Table 1.

Patient characteristics and treatments

COVID-19 ARDS Non-COVID-19 ARDS p value
Number of patients (n) 28 12 -
Males/females (n) 20/8 6/6 0•28
Age (years) 61 [55-72] 72 [54-79] 0•75
Body weight (kg) 80•0 [66•6-87•6] 86•5 [65•3-94•1] 0•71
Height (cm) 170 [164-175] 173 [169-175] 0•55
Body mass index (kg/m²) 26•3 [23•7-32•4] 28•9 [23•0-30•9] 0•79
SAPS II score in the first 24 hours 62 [49-68] 46 [40-57] 0•051
SOFA score in the first 24 hours 11 [7-12] 8 [5-12] 0•37
Comorbidities: (n (%))
  • 26-

    high blood pressure

11 (39) 6 (50) 0•73
  • 26-

    chronic obstructive pulmonary disease

2 (7) 1 (8) >0•99
  • 26-

    ischemic cardiac disease

5 (18) 3 (25) 0•68
  • 26-

    cancer

2 (7) 3 (25) 0•15
Treatments before admission: (n (%))
  • 26-

    glucocorticoids

1 (4) 3 (25) 0•073
  • 26-

    conversion enzyme inhibitors

5 (18) 1 (8) 0•54
  • 26-

    angiotensin antagonists

2 (7) 2 (16) 0•57
Interventions after admission: (n (%))
  • 26-

    catecholamines

17 (61) 4 (33) 0•17
  • 26-

    renal replacement therapy

9 (32) 0 (0) 0•038
Treatments after admission: (n (%))
  • 26-

    hydroxychloroquine

27 (96) 1 (8) <0•0001
  • 26-

    remdesivir

2 (7) 0 (0) >0•99
  • 26-

    lopinavir/ritonavir

7 (25) 0 (0) 0•081
  • 26-

    glucocorticoids

11 (39) 6 (50) 0•73
  • 26-

    fludrocortisone

1 (4) 4 (33) 0•022
  • 26-

    eculizumab

12 (43) 4 (33) 0•73
Body temperature at first sample (°C) 37•4 [36•5-38•3] 37•3 [36•8-37•8] 0•84
Respiratory rate at first sample (breaths per min) 26 [25-28] 20 [18-23] <0•0001
Tidal volume at first sample (mL) 420 [400-475] 438 [400-490] 0•99
Fraction of inspired oxygen at first sample (%) 80 [50-100] 48 [31-68] 0•007
Positive end-expiratory pressure at first sample (cm H2O) 10 [8-13] 5•5 [5-8] 0•0002
Serum creatinine at first sample (µM) 74 [56-137] 67 [44-86] 0•30
Serum C-reactive protein at first sample (mg/L) 195 [175-268] 76 [23-119] 0•002

Continuous data are presented as the median [IQR].