Fig. 2.

Pie charts displaying methylation alteration summaries of SNCA in different tissues or cell types and gene regions. Percentages refer to returned items in the database for a specific keyword that support the methylation alteration. The methylation alteration proportion of SNCA in PD patients versus controls are indicated as all tissues (A), substantia nigra (B), cortex (C), putamen (D), peripheral blood mononuclear cell (E), leukocyte (F), intron 1 (G), and promoter region (H), respectively. The methylation alteration information is defined as PD versus controls: Hypermethylation, No methylation alteration, No significant methylation alteration, and Hypomethylation. Alteration status was curated from the related papers.