Table 1.
Summary of cohort demographics and clinical symptoms
| Cohort 1 (discovery cohort) | Cohort 2 (recalled cohort) | Cohort 3 (validation cohort) | |||||
|---|---|---|---|---|---|---|---|
| PTSD + (n = 77) |
PTSD− (n = 74) |
PTSD + (n = 15) |
Subthreshold PTSD (n = 11) |
PTSD− (n = 29) |
PTSD + (n = 26) |
PTSD− (n = 26) |
|
| Age, years [mean (sd)] | 32.8 (7.4) | 32.6 (8.0) | 33.7 (8.2) | 35.6 (8.0) | 36.6 (8.9) | 36.8 (10.2) | 33.0 (8.2) |
| Race/ethnicity [n (%)] | |||||||
| Hispanic | 34 (44%) | 24 (32%) | 9 (60%) | 3 (27%) | 12 (41%) | 11 (42%) | 2 (8%) |
| Non-Hispanic Asian | 1 (1%) | 5 (7%) | 0 (0%) | 0 (0%) | 1 (3%) | 3 (12%) | 4 (15%) |
| Non-Hispanic black | 21 (27%) | 16 (22%) | 4 (27%) | 3 (27%) | 5 (17%) | 5 (19%) | 4 (15%) |
| Non-Hispanic white | 18 (23%) | 24 (32%) | 2 (13%) | 4 (36%) | 9 (31%) | 7 (27%) | 16 (62%) |
| Non-Hispanic other | 3 (4%) | 5 (7%) | 0 (0%) | 1 (9%) | 2 (7%) | 0 (0%) | 0 (0%) |
| Education [n (%)] | |||||||
| Less than 12th grade | 2 (3%) | 0 (0%) | 1 (7%) | 0 (0%) | 0 (0%) | 1 (4%) | 0 (0%) |
| HS diploma or GED | 27 (35%) | 13 (18%) | 2 (13%) | 1 (9%) | 4 (14%) | 10 (38%) | 6 (23%) |
| 2 years college, AA degree | 23 (30%) | 21 (28%) | 6 (40%) | 4 (36%) | 3 (10%) | 7 (27%) | 6 (23%) |
| 4 years college, BA degree | 22 (29%) | 28 (38%) | 5 (33%) | 4 (36%) | 19 (66%) | 5 (19%) | 7 (27%) |
| Master’s degree | 3 (4%) | 11 (15%) | 1 (7%) | 2 (18%) | 3 (10%) | 3 (12%) | 7 (27%) |
| Doctoral degree | 0 (0%) | 1 (1%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Body mass index [mean (sd)] | 30.1 (5.1) | 28.1 (4.3) | 32.2 (5.3) | 31.1 (8.0) | 27.2 (6.7) | 29.4 (6.7) | 26.9 (2.5) |
| Cholesterol [mean (sd)] | |||||||
| HDL cholesterol | 47.6 (11.9) | 50.1 (13.3) | 43.0 (8.0) | 45.9 (11.1) | 53.3 (13.9) | 47.3 (12.8) | 53.3 (11.9) |
| LDL cholesterol | 108.2 (32.3) | 100.0 (25.4) | 115.1 (26.4) | 110.3 (37.7) | 105.3 (27.6) | 116.2 (30.0) | 98.1 (31.2) |
| HbA1c [mean (sd)] | 5.4 (0.9) | 5.4 (0.4) | 5.6 (0.8) | 5.6 (0.7) | 5.3 (0.5) | 5.4 (0.3) | 5.3 (0.4) |
| PTSD Severity, Total CAPS [mean (sd)] | 68.0 (16.1) | 3.6 (4.9) | 69.5 (18.5) | 37.6 (9.0) | 5.2 (7.3) | 67.2 (19.4) | 2.7 (4.5) |
| Early trauma exposure, ETISR total [mean (sd)] | 7.7 (5.8) | 5.1 (4.0) | 5.2 (4.6) | 6.9 (4.8) | 4.5 (3.9) | 7.2 (4.8) | 4.9 (3.3) |
| Major depressive disorder [n (%)] | 42 (55%) | 0 (0%) | 9 (64%) | 2 (18%) | 0 (0%) | 9 (35%) | 1 (4%) |
| Peritraumatic dissociate experience, Rater version [mean (sd)] | 1.8 (0.4) | 1.2 (0.2) | 1.8 (0.5) | 1.8 (0.5) | 1.3 (0.3) | 1.8 (0.4) | 1.2 (0.2) |
| Peritraumatic distress inventory, Rater version [mean (sd)] | 2.1 (0.8) | 1.1 (0.6) | 2.2 (0.7) | 2.1 (0.9) | 1.0 (0.6) | 2.0 (0.9) | 1.0 (0.7) |
| Sleep quality, PSQI [mean (sd)] | 13.1 (3.3) | 5.9 (3.6) | 11.8 (3.5) | 10.7 (4.2) | 5.6 (3.0) | 11.9 (3.6) | 6.2 (3.3) |
| Number of tours [mean (sd)] | 1.8 (0.9) | 1.7 (0.8) | 1.5 (0.6) | 1.6 (0.7) | 1.9 (1.1) | 1.3 (0.6) | 2.1 (1.5) |