Table 1.

Characteristics of controls and AATD individuals.

Characteristic	PiMM (n=6)	PiZZ (n=6)	P-value
Age	48.5 (22–68)	51 (39–69)	0.82
Gender (M/F)	4/2	4/2	N/A
FEV1% predicted	86.6 (57–114)	60.8 (23.2–97)	0.14
FEV1/FVC	77.6 (59–91)	55.3 (31.6–71.8)	0.04
Current smoker	No	No	N/A

Definition of abbreviations: PiMM, individuals homozygous for normal PiM allele; PiZZ, individuals homozygous for mutant PiZ allele; N/A, not applicable; FEV1, forced expiratory volume in one second; FVC, forced vital capacity.