Table 2.
Comparison of sensitivity, specificity, positive and negative predictive values, and area under the ROC curve among different diagnostic markers used to identify Histoplasma spp. cultures (n = 104).
| Diagnostic markers | Sen (%) | Sp (%) | PPV (%) | PPV 95 % CI |
NPV (%) | NPV 95 % CI |
AUC | AUC 95 % CI |
AUC P-value |
|---|---|---|---|---|---|---|---|---|---|
| M-anti | 91.4 | 100 | 100 | 96.2–100 | 62.5 | 40.61–81.7 | 0.957 ± 0.0139 | 0.903–0.986 | <0.0001 |
| PCR220 | 98.1 | 100 | 100 | 96.4–100 | 88.3 | 63.6–98.5 | 0.990 ± 0.00677 | 0.952–1 | <0.0001 |
| PCR230 | 98.1 | 100 | 100 | 96.4–100 | 88.3 | 63.6–98.5 | 0.990 ± 0.00677 | 0.952–1 | <0.0001 |
Sen, sensitivity; Sp, specificity; PPV, positive predictive value; NPV, negative predictive value; AUC, area under the curve.