Table 1.
Clinical findings.
| Clinical Findings | Case1 | Case 2 | Case 3 |
|---|---|---|---|
| Age of diagnosis | 7.5 years | 4 years | 8 years |
| Age at which rapid weight gain began | 5 years | 3 years | 5 years |
| Follow-up period | 37 months | 24 months | 4 months |
| Hypothalamic dysfunction | Hyperprolactinemia | Hyperprolactinemia | Hypernatremia |
| Deficiency of growth hormone | |||
| Sleep disordered breathing | CO2 retention in arterial blood gas analyses during sleeping | Polysomnography | CO2 retention in arterial blood gas analyses during sleeping |
| Autonomic dysfunctions | Abnormal pupil reflex | – | Excessive sweating |
| Heart rate irregularity | Decreased pain sensitivity | ||
| Neural crest tumor | – | Ganglioneuroma | - |
| Mood disorder | + | – | + |