Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 20;10:587237. doi: 10.3389/fonc.2020.587237

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Ye, Li, Huang, Zhang and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effect of the DNA vaccine on tumor growth: The mean volume of the tumor mass in the control group (immunized with pcDNA3.1, n=6) was much larger than that of the pcDNA3.1-CS1 (n=6) and pcDNA3.1-CS1/CRT group (n=6). The group mean tumor volumes were significantly different between the two experiment groups and the control group (mean ± SD. P < 0.01, respectively), and there was also significant difference between the CS1 and CS1/CRT group (mean ± SD. P < 0.05), when the booster injection was administrated on D18 (seven days after the first injection). DNA vaccines significantly suppressed the growth of myeloma cells and the inhibition of the CS1/CRT fusion DNA vaccine on the tumor cells was more obvious than that of the CS1 vaccine.