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. 2020 Nov 20;10:574939. doi: 10.3389/fonc.2020.574939

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Copyright © 2020 Zhu, Tao, Lin, Tang and Hu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of hub IRGs and their molecular characteristics. (A) PPI network of the 24 hub IRGs. (B) The relationship between gene node degree and the number of nodes. (C) Mean expression differences of hub IRGs between AML and normal controls. (D) Cluster graph of 24 hub IRGs in the AML samples. The darker red color represents a higher level of gene expression, while the darker blue color represents a lower level of gene expression. (E) Hazard ratios (HR) show the prognostic value of the hub IRGs. A Gene with a HR of greater than 1 indicates a risk factor for prognosis, while a HR of less than 1 indicates a protective effect.