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Functional enrichment signatures of colorectal cancer (CRCs) under hypoxic conditions. (A–D) Gene set enrichment analyses (GSEA) enrichment hallmarks visualized as volcano plots in The Cancer Genome Atlas (TCGA), GSE14333, GSE17538, and GSE39582, respectively. Hallmarks significantly correlated with hypoxia or normoxia were labeled with red and blue dots, respectively. NES, normalized enrichment score.
