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. 2020 Nov 20;7:214. doi: 10.3389/fmolb.2020.00214

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Copyright © 2020 Koopman and Rüdiger.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Both neuronal and glial cells present in analyzed sample. Heat map of neuronal and glial protein markers in different brain regions, differently affected in Alzheimer’s Disease. Numbers represent the fold change in AD brains versus controls, indicated per brain region (blue gradient; white, no change; decrease, red gradient). Gray boxes represent unavailable data. FDR values are indicated as percentage. (A) Protein markers for all glial cells are present in all six brain regions, indicating presence of these types of cells in the analyzed sample. (B) Protein markers for glutamatergic (excitatory) neurons and GABAergic (inhibitory) neurons, indicating presence of both type of neurons in analyzed brain tissue.