Table 4.
Univariate and multivariable analysis of prognostic factors for 5-year survival in LUAD and LUSC.
| LUAD | LUSC | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariate analysis | Multivariate analysis (adjusted for age) | Univariate analysis | Multivariate analysis | |||||||||
| HR | P >|z| | 95% CI | HR | P >|z| | 95% CI | HR | P >|z| | 95% CI | HR | P >|z| | 95% CI | |
|
GPR115
High vs. Low |
2.192 | 0.001* | 1.401–3.428 | 1.706 | 0.039* | 0.940–3.097 | 1.735 | 0.193 | 0.833–2.442 | |||
|
Age (years)
≤60 vs. >60 |
1.223 | 0.364 | 0.792–1.887 | 0.818 | 0.477 | 0.471–1.422 | ||||||
|
Gender
1 vs. 2 |
0.516 | 0.003* | 0.333–0.798 | 0.485 | 0.028* | 0.254–0.926 | 0.902 | 0.842 | 0.327–2.489 | |||
|
Smoking
No vs. Yes |
2.517 | 0.003* | 1.378–4.595 | 1.615 | 0.201 | 0.755–3.367 | 0.804 | 0.531 | 0.407–1.589 | |||
|
Differentiation
1 vs. 2 vs. 3 |
2.410 | <0.001* | 1.578–3.681 | 1.914 | 0.026* | 1.081–3.391 | 0.850 | 0.482 | 0.540–1.337 | |||
|
TNM stage
1 vs. 2 vs. 3 |
1.814 | <0.001* | 1.374–2.395 | 1.018 | 0.967 | 0.439–2.357 | 1.823 | <0.001* | 1.312–2.531 | 1.481 | 0.167 | 0.848–2.585 |
|
T
1 vs. 2 vs. 3 |
1.910 | <0.001* | 1.340–2.722 | 1.212 | 0.542 | 0.653–2.247 | 0.964 | 0.871 | 0.621–1.497 | |||
|
N
0 vs. 1 vs. 2 |
1.709 | <0.001* | 1.331–2.195 | 1.715 | 0.107 | 0.889–3.309 | 1.744 | <0.001* | 1.287–2.363 | 1.278 | 0.354 | 0.761–2.144 |
|
M
M0 vs. M1 |
1.137 | 0.857 | 0.028–4.626 | 4.229 | 0.159 | 0.567–31.521 | ||||||
*P < 0.05.
Gender 1, Male, Gender 2, Female.
Differentiation 1, well; Differentiation 2, Middle; Differentiation 3, Poor.
TNM 1, IA and IB; TNM 2, IIA and IIB; TNM 3, IIIA, IIIB, and IV.