Table 1.
Top 10 regulated proteins in four treatments with P-value lower than 0.05
| T1 (5 μM_6 h) vs Ctrl |
T2 (5 μM_6 h) vs Ctrl |
T3 (25 μM_6 h) vs Ctrl |
T4 (25 μM_6 h) vs Ctrl |
|||||
|---|---|---|---|---|---|---|---|---|
| Gene ID | FC | Gene ID | FC | Gene ID | FC | Gene ID | FC | |
| Up-regulated (Treatment vs. Ctrl) | UBE2W | 3.128 | TNFAIP8 | 2.218 | COPS9 | 2.079 | RFXANK | 2.433 |
| HIST1H1E | 2.574 | RNF121 | 1.419 | FLG2 | 1.864 | PHOSPHO2 | 1.924 | |
| COPS9 | 1.976 | SET | 1.369 | RAD51D | 1.732 | CALR3 | 1.804 | |
| HMOX1 | 1.924 | UQCR11 | 1.337 | HMOX1 | 1.671 | NEDD4L | 1.748 | |
| CDH6 | 1.716 | TAF1 | 1.322 | ZNF384 | 1.604 | TNFAIP8 | 1.724 | |
| CCDC138 | 1.711 | SERBP1 | 1.319 | KRT17 | 1.482 | TAF8 | 1.536 | |
| C15orf41 | 1.667 | GPC6 | 1.314 | SLC35F6 | 1.479 | CALU | 1.510 | |
| C8B | 1.640 | NDUFAF2 | 1.288 | BRD9 | 1.427 | KRT6A | 1.445 | |
| C9 | 1.621 | APOO | 1.283 | OGFOD2 | 1.410 | TAF1 | 1.416 | |
| KLC1 | 1.616 | ATG4A | 1.276 | ADGRE5 | 1.390 | SGO1 | 1.362 | |
| Down-regulated (Treatment vs. Ctrl) | MT1G | –4.718 | RBX1 | –1.735 | MT1G | –2.752 | CFB | –1.742 |
| ING1 | –2.757 | CPNE4 | –1.683 | JPT1 | –2.368 | JPT1 | –1.687 | |
| NPC2 | –1.975 | NOTCH3 | –1.599 | POLL | –1.887 | XRCC2 | –1.617 | |
| HPCAL1 | –1.935 | CFI | –1.533 | PCNP | –1.579 | RAP2A | –1.554 | |
| DECR1 | –1.787 | LTF | –1.530 | GM2A | –1.487 | HSP90AB4P | –1.554 | |
| GM2A | –1.735 | AHSG | –1.452 | CYCS | –1.478 | DLX2 | –1.491 | |
| SMIMI5 | –1.643 | COL1A1 | –1.380 | FUBP1 | –1.471 | MMGT1 | –1.474 | |
| CELF2 | –1.625 | CHIA | –1.348 | BOLA1 | –1.410 | B4GALT7 | –1.435 | |
| GPR155 | –1.614 | PLXDC2 | –1.338 | DEPTOR | –1.406 | ZFP36L2 | –1.418 | |
| TXN | –1.602 | PLEKHA8 | –1.331 | SERGEF | –1.403 | HNRNPAB | –1.416 | |
The red and blue colors represent the top ten up- and down-regulated proteins respectively. Ctrl: Control; FC: fold change.