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. 2020 May 11;15(11):2016–2026. doi: 10.4103/1673-5374.282218

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Copyright: © 2020 Neural Regeneration Research

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Overview of OEC collection, characteristics and purification.

OECs can be obtained from biopsies taken either from olfactory mucosa or olfactory bulb. The figure shows all the different cell types that can be found in each type of biopsy and various markers reported to be expressed by each cell type. The figure also summarizes different methods of purification depending on the source of cells and reported proportions of OECs acquired as a result of purification. AC: Astrocytes; FB: fibroblasts; FBm: meningeal fibroblast; GFAP: glial fibrillary acid protein; HNK1: human natural killer antigen-1; IBA1: ionised calcium binding adapter molecule 1; MG: microglia; MSC: mesenchymal stem cell; NB: neuronal cell bodies; NT-3: neurotrophin-3; OB: olfactory bulb; ODC: oligodendrocytes; OEC: olfactory ensheathing cells; OM: olfactory mucosa; RE: respiratory epithelium; SC: Schwann cells; O4: oligodendrocyte marker 4; p75^NTR: p75 neurotrophin receptor; SOX10: Sry-related HMG-Box gene 10; Thy1: thymus cell antigen 1; TUJ1: neuron-specific class III β-tubulin.