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. 2020 Nov 1;13(11):2788–2805.

Table 2.

The top 20 genes most closely related to the seven hub genes in LUSC

No. GBP1 ITGAM CSF1 SPP1 COL1A1 LAMB1 THBS1







genes CC genes CC genes CC genes CC genes CC genes CC genes CC
1 GBP2 0.77 SH2B3 0.73 GPR84 0.73 CBR3 0.61 COL5A1 0.96 FSTL1 0.61 BICC1 0.70
2 BATF2 0.75 NFAM1 0.69 CSF1R 0.72 SRXN1 0.59 COL3A1 0.95 LEPRE1 0.59 CRISPLD2 0.70
3 STAT1 0.75 ITGB2 0.68 CACNA2D4 0.68 GCLM 0.57 COL6A3 0.92 FN1 0.56 ITGA1 0.67
4 TAP1 0.74 DOCK10 0.68 CLEC5A 0.67 EPHX1 0.56 COL1A2 0.91 LTBP1 0.54 CTGF 0.63
5 UBE2L6 0.73 LGALS9 0.67 HIC1 0.65 PRDX1 0.55 COL5A2 0.91 LAMC1 0.54 CYR61 0.62
6 IRF1 0.73 PILRA 0.66 CD14 0.65 GSR 0.55 PDGFRB 0.9 TCF7L1 0.53 SPON1 0.62
7 GBP5 0.73 SIGLEC9 0.66 RNASE2 0.64 OSGIN1 0.54 ADAMTS2 0.89 CRIM1 0.53 IL1R1 0.61
8 GBP4 0.71 NCKAP1L 0.66 AGAP2 0.63 AKR1B10 0.52 SPARC 0.88 LAMA5 0.53 LAMA4 0.61
9 APOL6 0.70 IL21R 0.65 STAB1 0.62 G6PD 0.51 NID2 0.87 PXDN 0.52 GREM1 0.61
10 PRF1 0.68 HK3 0.65 ABI3 0.62 NQO1 0.51 BGN 0.87 AFAP1 0.52 LRRC32 0.61
11 LAP3 0.68 FCGR2C 0.64 ADAP2 0.62 AKR1C3 0.51 COL11A1 0.87 RBM9 0.52 MRVI1 0.60
12 PSMB9 0.68 TNFRSF1B 0.64 CD300C 0.62 MAP2 0.49 COL6A2 0.87 C1QTNF6 0.52 FGF7 0.60
13 CXCL9 0.67 LILRB4 0.64 ENG 0.62 CBR1 0.49 MMP2 0.86 LATS2 0.52 COL6A3 0.60
14 PSME2 0.67 LRRC25 0.64 LRRC25 0.62 CYP4F3 0.49 LRRC15 0.86 FBLN1 0.52 ACTA2 0.60
15 CCL4 0.67 SPI1 0.63 TNFRSF1B 0.61 CES1 0.49 AEBP1 0.86 ARHGEF17 0.51 ZEB2 0.60
16 IL18BP 0.66 STAT5A 0.63 COL8A1 0.61 ME1 0.49 THBS2 0.85 CDK14 0.50 C13orf33 0.60
17 B2M 0.65 CD4 0.63 NLRP3 0.61 TXNRD1 0.48 TIMP2 0.85 GLI3 0.50 NID2 0.59
18 LAG3 0.65 CD74 0.63 SIGLEC9 0.61 ASPH 0.48 ZNF469 0.85 IGDCC4 0.50 CD93 0.59
19 WARS 0.65 HLA-DOA 0.62 ITGB7 0.60 AKR1C1 0.47 FNDC1 0.84 KIAA1462 0.49 PMP22 0.59
20 HLA-E 0.65 CLEC5A 0.62 SLC7A7 0.59 TDP2 0.47 POSTN 0.84 TGFB3 0.49 COL3A1 0.59

Note: CC correlation coefficient.