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. 2020 Nov 1;10(11):3508–3531.

Figure 4.

Figure 4

SCFAs regulate chemotherapy- or radiotherapy-associated intestinal microbial dysbiosis and repair the intestinal barrier. Applying SCFAs directly or SCFA-producing bacteria regained intestinal homeostasis and ordered the milieu by increasing the proportions of beneficial bacteria and reducing the number of pathogenic bacteria. Thereupon, the recovered mucus layer and reduced intestinal permeability also emerged. SCFAs, short chain fatty acids; ↑, increased; ↓, decreased.