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PAI1 is involved in ERRα regulated cell proliferation, migration and invasion of PC cells. A-C. CCK-8, colony formation and EdU assays were performed to evaluate the cell proliferation of PC cells with PAI1 knockdown and/or ERRα overexpression. D and E. Knockdown of PAI1 significantly inhibited the migration and invasion abilities of PC cells, and abolished those abilities enhanced by ERRα overexpression. *P<0.05, **P<0.01, ***P<0.001.
