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. 2020 Nov 1;10(11):3852–3866.

Table 2.

Outcomes of patients

Parameter Total (n = 45) SCT (n = 17) P (SCT vs. Chemo) MST (n = 11) P (SCT vs. MST) Chemo (n = 17) P (MST vs. Chemo)
Median time of ANC recovery (range), days 12 (8-18) 9 (8-14) < .001 12 (10-17) < .001 12 (10-18) .462
Median time of platelet recovery (range), days 13 (6-18) 10 (6-15) < .001 13.5 (7-18) < .001 13 (10-18) .969
Severe adverse event, n (%) < .001 < .001 .132
    Severe infections 6 (13) 2 (12) 0 (0) 4 (24)
    III-IV aGVHD 2 (4) 2 (12) 0 (0) 0 (0)
    Organ failure 6 (13) 6 (35) 0 (0) 0 (0)
Early death, n (%) 1 (2) 1 (6) .476 0 (0) .804 0 (0) .804
Total death, n (%) 24 (53) 11 (65) .486 4 (36) .142 9 (53) .390
Causes of death, n (%) .067 .062 < .999
    Relapse 13 (27) 2 (12) 4 (36) 7 (41)
    Infections 4 (9) 3 (18) 0 (0) 1 (6)
    GVHD 2 (4) 2 (12) 0 (0) 0 (0)
    Organ failure 5 (11) 4 (24) 0 (0) 1 (6)
OS, No. of Events (%) 24 (47) 11 (31) .253 4 (47) .046 9 (24) .022
    2-year OS 14 (69) 10 (39) .018 1 (91) .012 3 (80) .492
    4-year OS 20 (56) 11 (31) .159 1 (91) .005 8 (36) .013
LFS, No. of Events (%) 27 (40) 11 (33) .580 6 (41) .111 10 (31) .060
    2-year LFS 21 (53) 11 (33) .428 1 (91) .005 9 (41) .017
    4-year LFS 24 (47) 11 (33) .580 3 (72) .021 10 (31) .023
Hematologic relapse, No. of Events (%) 18 (40) 3 (20) .148 6 (59) .585 9 (67) .083
    2-year relapse 12 (27) 3 (20) .226 1 (9) .429 8 (56) .025
    4-year relapse 15 (33) 3 (20) .148 3 (28) .847 9 (67) .034
NRM, No. of Events (%) 9 (20) 8 (47) .008 0 (0) .008 1 (6) .421
    1-year NRM 8 (18) 7 (41) .019 0 (0) .018 1 (6) .421
    2-year NRM 9 (20) 8 (47) .008 0 (0) .008 1 (6) .421

Abbreviations: SCT, stem cell transplantation; MST, microtransplantation; Chemo, Chemotherapy; ANC, absolute neutrophil count; aGVHD, acute graft-versus-host disease; OS, overall survival; LFS, leukemia-free survival; NRM, non-relapse mortality.