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Proposed pathways for the colonic metabolism of EC. Structures in blue color were detected in the present study. The chemicals in the red boxes [i.e., 1-(3′,4′-dihydroxyphenyl)-3-(2″,4″,6″-trihydroxyphenyl)-2-propanol (3,4-diHPP-2-ol) and 5-(3′,4′-dihydroxyphenyl)-γ-valerolactone (3,4-diHPV)] were the major metabolites formed in the time-dependent in vitro fecal incubation.
