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. 2020 Nov 20;23(1):74. doi: 10.3892/mmr.2020.11712

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — PFKP promotes glycolysis of NSCLC cells. (A) Relative glucose uptake. (B) Relative lactate production. (C) ATP/ADP ratio. (D) Expression levels of glycolysis-associated enzymes (HK-2, LDHA and Glut-1) were detected by western blot analysis. Data are presented as mean ± SD from three independent experiments. **P<0.01 vs. control group; ^##P<0.01 vs. si-NC group; ^$$P<0.01 vs. pCMV6-ENTRY group. PFKP, platelet isoform of phosphofructokinase; ATP, adenosine triphosphate; ADP, adenosine diphosphate; HK-2, hexokinase-2; LDHA, lactate dehydrogenase A; Glut-1, glucose transporter-1; si, small interfering RNA; NC, negative control.