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. 2020 Nov 23;23(1):85. doi: 10.3892/mmr.2020.11724

Figure 2.

Figure 2.

miR-204-5p expression is downregulated in GC tissues and cell lines, and its expression levels are negatively correlated with those of SNHG4. (A) Possible complementary sequences in SNHG4-WT and miR-204-5p. Relative luciferase activity in (B) AGS and (C) HGC-27 cells treated with or without miR-204-5p inhibitor when SNHG4 sequence was WT or MUT. (D) Relative miR-204-5p expression levels in ANTs or GC tissues. Correlation between the expression levels of SNHG4 and miR-204-5p in (E) ANT and (F) GC tissues. (G) Relative miR-204-5p expression levels in GES-1, SNU719, AGS and HGC-27 cell lines. Bars indicate the mean ± standard deviation. ***P<0.001 vs. IC; ^^^P<0.001 vs. ANT; ###P<0.001 vs. GES-1. SNHG4, small nucleolar RNA host gene 4; GC, gastric cancer; miR, microRNA; WT, wild-type; MUT, mutant; ANT, adjacent normal tissues; IC, inhibitor control.