Table 6.
Predicted genes associated with subsystems of pathogenesis and environmental adaption.
| Gene Subsystem Category and Name | Presence/Absence of Gene in V. anguillarum J360 | GenBank Accession N° | |
|---|---|---|---|
| Chromosome-I | Chromosome-II | ||
| Iron transport and regulation | |||
| iron-regulated protein A | X | DYL72_00705 | |
| tonB2, exbD2 | X | DYL72_00755, DYL72_00745 | |
| tonB1, exbB, exbD1 | X | DYL72_00260, DYL72_00265, DYL72_00270 | |
| fur | X | DYL72_03070 | |
| iron ABC transport permease | X | DYL72_00175, DYL72_00765 | |
| Heme transport | |||
| Ton-B-dependent hemoglobin receptor | X | X | DYL72_17445, DYL72_00730, DYL72_20920 |
| hutXZ | X | DYL72_00735, DYL72_00740 | |
| heme ABC transporter protein | X | DYL72_00770, DYL72_02835 | |
| heme exporter protein ccmBD | X | DYL72_02830, DYL72_02840 | |
| Ferrous and ferric transport | |||
| ferric ABC transporter | X | DYL72_00180 | |
| feoABC | X | DYL72_02945, DYL72_02940, DYL72_02935 | |
| Ferrichrome | |||
| fhuACBD | X | DYL72_06770, DYL72_10590 | |
| Hemolysins | |||
| hemolysin genes | X | X | DYL72_01800, DYL72_07805, DYL72_12295, DYL72_17765 |
| thermolabile hemolysin | X | DYL72_17760 | |
| Toxins-associated genes | |||
| toxins and pseudogenes | X | DYL72_00035, DYL72_00045, DYL72_14975, DYL72_14985 | |
| rtxA, hipA | X | DYL72_01180, DYL72_03440 | |
| ampC | X | DYL72_17850 | |
| type II toxin–antitoxin system RelBE/ParDE/DinJ family | X | DYL72_18560, DYL72_18565, DYL72_18715, DYL72_18750, DYL72_19140, DYL72_19250, DYL72_19960 | |
| type II toxin–antitoxin system prevent-host-death family antitoxin | X | DYL72_18805 | |
| Txe/YoeB family addiction module | X | DYL72_18810 | |
| type II toxin–antitoxin system Phd/YefM family antitoxin | X | DYL72_19255 | |
| type II toxin–antitoxin system YafQ family toxin | X | DYL72_19965 | |
| toxin–antitoxin system subunit antitoxin | X | DYL72_20370 | |
| Metalloproteases | |||
| CPBP family intramembrane metalloprotease | X | DYL72_00295 | |
| pmbA, tldD, ftsH | X | DYL72_05300, DYL72_09550, DYL72_10735 | |
| SprT family zinc-dependent metalloprotease | X | DYL72_09830 | |
| M6 family metalloprotease domain-containing protein | X | DYL72_17780 | |
| Secreted enzymes | |||
| phospholipase gene | X | DYL72_16230 | |
| lipase | X | DYL72_17465, DYL72_18050, DYL72_20375 | |
| Motility and Chemotaxis | |||
| fliRQPONMLKJIHGFE, fliSTD, fliL | X | DYL72_03140-DYL72_03205, DYL72_03225-DYL72_03235, DYL72_08330 | |
| motYA, motB | X | DYL72_12660, DYL72_00275, DYL72_12090 | |
| flhFAB | X | DYL72_02900, DYL72_02905, DYL72_03135, | |
| flag, flaCA | X | DYL72_03240, DYL72_03670, DYL72_03675 | |
| flagellin | X | DYL72_03245, DYL72_03250, DYL72_03255 | |
| flgLKJIHGFEDCB, flgAMNP | X | DYL72_03685-DYL72_03735, DYL72_03750-DYL72_03765 | |
| flagellar basal-body protein | X | DYL72_03775 | |
| pomA | X | DYL72_12085 | |
| flagellar brake protein | X | DYL72_17355, DYL72_20195 | |
| methyl-accepting chemotaxis protein | X (17) | X (16) | |
| chemotaxis response regulator protein-glutamate methylesterase | X | X | DYL72_00595, DYL72_02870, DYL72_16590, |
| cheD, cheW, cheA, cheV, cheY, cheX, cheC | X | X | DYL72_00600, DYL72_00610, DYL72_00620, DYL72_01045, DYL72_02885, DYL72_09235, DYL72_20035 |
| cheV2, cheW2, cheW3, cheA2, cheV3, cheD2, cheW4, cheW5, cheA3, cheV4 | X | X | DYL72_02435, DYL72_02855, DYL72_02860, DYL72_02875, DYL72_03745, DYL72_16595, DYL72_16610, DYL72_16615, DYL72_16620, DYL72_21345 |
| chemotaxis protein | X | X | DYL72_00635, DYL72_16275, DYL72_16460 |
| chemotaxis protein methyltransferase | X | DYL72_03740 | |
| Type IV pilus | |||
| pilQ, pilW, pilM, pilT, pilB | X | DYL72_05800, DYL72_01100, DYL72_05820, DYL72_09795, DYL72_10350 | |
| Type VI secretion system (T6SS) | |||
| tssI, tssBCEFG, tssJ, tssK tssH, tssAM | X | DYL72_16415, DYL72_17000—DYL72_17020, DYL72_17030, DYL72_17045, DYL72_17055, DYL72_17070, DYL72_17075, | |
| tssI2, tssM2, tssKJHFE2, tssC2, tssI3, tssI4, tssI5, tssI6 | X | X | DYL72_17085, DYL72_21115, DYL72_00885, DYL72_00895, DYL72_00900, DYL72_00930, DYL72_00940, DYL72_00945, DYL72_00955, DYL72_00960, DYL72_00975, DYL72_02685, DYL72_10015 |
| tagHO | X | DYL72_17025, DYL72_17065 | |
| Hcp family type VI secretion system effector | X | X | DYL72_16420, DYL72_18695, DYL72_21120, DYL72_02690, DYL72_10010 |
| type VI secretion system tube protein Hcp | X | DYL72_00965 | |
| DotU family type IV/VI secretion system protein | X | X | DYL72_17050, DYL72_00890 |
| type VI secretion protein | X | X | DYL72_17080, DYL72_00950, DYL72_00970, DYL72_00985 |
| type VI secretion system PAAR protein | X | X | DYL72_21095, DYL72_02650, DYL72_02660, DYL72_10045, |
| type VI secretion protein VasB-1 | X | DYL72_00935 | |
| Quorum sensing | |||
| quorum-sensing autoinducer synthase | X | DYL72_17995 | |
| Regulators | |||
| transcriptional regulator LuxR | X | X | DYL72_06050, DYL72_21285 |
| transcriptional regulator LysR | X | DYL72_03060, DYL72_09990 | |
| transcriptional regulator XRE | X | DYL72_10570 | |
| cysB | X | DYL72_13470 | |
| nhaR | X | DYL72_10935 | |
| hfq | X | DYL72_09115 | |