Fig. 3.

Log transformed pen mean M. hyopneumoniae colony forming units (cfu) in bronchoalveolar lavage and log transformed pen mean P. multocida cfu in lung tissue recovered at necropsy in Mhyop + Pm dual-challenge study for tylvalosin pigs (TVN group) and untreated pigs (CTL group). Box plots represents the arithmetic mean of each pen. There were 4 pigs in each pen, 11 pens for each treatment. Pigs were challenged on Day 0, Day 1 and Day 3 with broth media containing 1 × 10⁹ cfu of M. hyopneumoniae in 5 ml of Mhyop and on Day 14 with broth media containing 1 × 10¹⁰ cfu in 10 ml of P. multocida. Both challenges through intranasal route and scored on Day 28. P values from least square means derived from statistical models