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. 2020 Dec 4;21:527. doi: 10.1186/s12882-020-02183-z

Fig. 4.

Fig. 4

Effect of CSE/H2S system on TGF-β protein expression and Smad3 phosphorylation. Representative results of Western blot demonstrated the changes in TGF-β protein expression and Smad3 phosphorylation levels in the sham, UAAS, UAAS+NaHS and UAAS+PPG groups (a, c); Quantitative analysis (b, d) showed that TGF-β protein expression and Smad3 phosphorylation levels decreased significantly in UAAS mice, but NaHS treatment attenuated the UAAS-induced inhibition on TGF-β protein expression and Smad3 phosphorylation levels, and PPG treatment aggravated the decrease of TGF-β protein expression and Smad3 phosphorylation levels (*P < 0.05 vs. sham group, #P < 0.05 vs. UAAS group, and &P < 0.05 vs. UAAS group, n = 6 per group)