Table 1.

Characteristics of interventional studies

Author, Year	Location	Sample size	Age range	Duration	Study Design	DAM	PMSAM	calcium dosage	Calcium type	Adjustment	Result	Quality score
Thys-Jacobs et al., 1989	USA	60	35.1±6	3 months	RCT	Food record	PDSR	1000 mg daily	Calcium carbonate	Baseline symptoms score	Negative affect, water retention and pain reduced significantly	High
Thys-Jacobs et al., 1998	USA	497	32.8±6.7	3 months	RCT	-	PMS Diary	1200 mg daily	Calcium carbonate	-	Total symptoms score reduced significantly	High
Ghanbari et al., 2009	Iran	179	21.4±3.6	3 months	RCT	-	-	500 mg twice daily	Calcium carbonate	-	Tiredness, Appetite and Depressive symptoms reduced significantly	Low
Yonkers et al., 2013	USA	39	25-45	4 months	RCT	-	Daily Record of Severity of Problems	600 mg twice daily	Calcium carbonate	-	NS	High
Bharati et al., 2016	India	58	18-22	3 months	Quasi-experimental	-	-	500 mg daily	Calcium carbonate	-	Number and severity of PMS symptoms reduced significantly	Low
Samieipour et al., 2016	Iran	210	20.32±8.92	2 months	RCT	-	PMS symptoms questionnaire	500 mg daily	Calcium carbonate		Physical, psychological and general symptoms of PMS reduced significantly	High
Masoumi et al., 2016	Iran	76	21±2.06	2 months	RCT	-	PDSR	500 mg twice daily+ 40 mg vitamin B6	-	-	Physical, psychological and general symptoms of PMS reduced significantly	Low
Shobeiri et al., 2017	Iran	66	20.95±1.19	2 months	RCT	-	Daily Record of Severity of Problems	500 mg daily	-	-	anxiety, depression, emotional changes, water retention, and somatic changes reduced significantly	High

DAM=Dietary Assessment Method, MSAM=Premenstrual Syndrome Assessment Method, PMS=Premenstrual Syndrome, RCT=Randomized clinical trial, PDSR=PMS Daily Symptom Record, GHQ-28=General Health Questionnaires-28, COPE=Calendar of Premenstrual Experiences, PSST=Premenstrual Syndrome Screening Tool, IU=International Unit