Table II.
The others results of meta-analysis.
| P-value | |||||||
|---|---|---|---|---|---|---|---|
| Index | Interventions | RR (95% CI) | bP-value | I2, % | cP-value | Begg's | Egger's |
| Vaginal delivery | Overall | 1.37 (0.63-3.00) | 0.022 | 80.9 | 0.432 | 1.000 | - |
| HA vs. II | 2.07 (1.19-3.62) | - | - | 0.011 | - | - | |
| A vs. Pl | 0.95 (0.64-1.42) | - | - | 0.802 | - | - | |
| Cesarean delivery | Overall | 1.09 (0.68-1.75) | 0.346 | 10.5 | 0.729 | 0.462 | 0.574 |
| HA vs. A | 0.75 (0.38-1.47) | - | - | 0.402 | - | - | |
| HA vs. II | 2.39 (0.71-8.05) | 0.187 | 42.6 | 0.159 | 0.317 | - | |
| A vs. Pl | 1.13 (0.48-2.65) | 0.750 | 0.0 | 0.788 | 0.317 | - | |
| Intrauterine death | HA vs. II | 0.44 (0.07-2.79) | 0.387 | 0.0 | 0.382 | 1.000 | - |
| Gestational age at birth | Overall | 1.24 (-0.46-2.93)a | 0.000 | 97.9 | 0.154 | 0.764 | 0.976 |
| HA vs. A | 0.04 (-1.66-1.73)a | 0.000 | 94.7 | 0.967 | 0.602 | 0.936 | |
| HA vs. II | 0.40 (-1.00-1.80)a | - | - | 0.577 | - | - | |
| HA vs. Pl | 4.11 (3.68-4.53)a | 0.925 | 0.0 | <0.001 | 0.317 | - | |
| A vs. Pl | 0.00 (-0.49-0.49)a | - | - | 1.000 | - | - | |
| IUGR | Overall | 0.42 (0.20-0.88) | 0.267 | 18.7 | 0.021 | 1.000 | - |
| HA vs. Pl | 0.33 (0.14-0.80) | - | - | 0.014 | - | - | |
| A vs. Pl | 0.89 (0.20-3.96) | - | - | 0.873 | - | - | |
| Miscarriages | Overall | 0.60 (0.49-0.73) | 0.033 | 49.2 | 0.000 | 0.436 | 0.437 |
| HA vs. A | 0.59 (0.40-0.87) | 0.605 | 0.0 | 0.007 | 0.602 | 0.703 | |
| A vs. Pl | 1.20 (0.80-1.81) | 0.862 | 0.0 | 0.382 | 0.317 | - | |
| HA vs. Pl | 0.47 (0.33-0.67) | 0.946 | 0.0 | <0.001 | 0.317 | - | |
| HA vs. Apr | 0.35 (0.12-1.01) | - | - | 0.051 | - | - | |
| H vs. Apr | 0.32 (0.17-0.62) | 0.962 | 0.0 | 0.001 | 0.317 | - | |
| H vs. Pl | 0.20 (0.03-1.56) | - | - | 0.125 | - | - | |
| Gestational diabetes | |||||||
| Overall | 0.26 (0.06-1.14) | 0.966 | 0.0 | 0.073 | 1.000 | - | |
| A vs. Pl | 0.25 (0.03-2.07) | - | - | 0.199 | - | - | |
| H vs. Pl | 0.27 (0.03-2.10) | - | - | 0.209 | - | ||
| Thrombocytopenia | |||||||
| Overall | 0.69 (0.30-1.57) | 0.798 | 0.0 | 0.373 | 0.806 | 0.373 | |
| HA vs. A | 0.51 (0.16-1.63) | 0.698 | 0.0 | 0.255 | 0.602 | 0.899 | |
| HA vs. Pl | 0.50 (0.05-5.22) | - | - | 0.563 | - | - | |
| HA vs. Apr | 1.27 (0.30-5.35) | - | - | 0.742 | - | - | |
| Pre-eclampsia | |||||||
| Overall | 0.51 (0.31-0.87) | 0.936 | 0.0 | 0.012 | 0.260 | 0.438 | |
| HA vs. A | 0.52 (0.05-5.40) | - | - | 0.581 | - | - | |
| HA vs. Pl | 0.48 (0.25-0.93) | 0.582 | 0.0 | 0.029 | 0.317 | - | |
| A vs. Pl | 0.58 (0.24-1.43) | 0.666 | 0.0 | 0.240 | 0.602 | 0.643 | |
aAnalyzed by WMD (95% CI).
bP-value of heterogeneity χ2;
cP-value of pooled statistic. H, heparin alone, A, aspirin alone; HA, heparin combined with aspirin; II, intravenous immunoglobulin; Pl, placebo; Pr, prednisone; APr, aspirin and prednisone; WMD, weighted mean difference; RR, relative risk; IUGR, intrauterine growth restriction.