Table II.
Correlation of the clinicopathologic findings with TFF3 expression in the CRC cases.
| Characteristic | TFF3 low (score ≤4.75) | TFF3 high (score >4.75) | χ2 or Fisher's exact test P-value |
|---|---|---|---|
| Sex | |||
| Male | 40 | 5 | 0.656 |
| Female | 36 | 6 | |
| Race/ethnicity | |||
| African-Americans | 46 | 5 | 0.383 |
| Non-Hispanic Caucasians | 30 | 6 | |
| Site | |||
| Colon | 31 | 29 | 0.819 |
| Rectum | 13 | 14 | |
| TNM stage | |||
| I | 9 | 2 | 0.120 |
| II | 21 | 6 | |
| III | 30 | 1 | |
| IV | 16 | 2 | |
| Histological grade | |||
| Well-differentiated | 2 | 2 | 0.026a |
| Moderately differentiated | 64 | 7 | |
| Poorly differentiated | 5 | 2 | |
| Lymph node metastasis | |||
| Negative | 25 | 7 | 0.081 |
| Positive | 44 | 3 | |
| Surgical margins | |||
| Negative | 57 | 10 | 0.682 |
| Positive | 15 | 1 |
a
Significant difference, P<0.05. TFF3, trefoil factor 3; CRC, colorectal cancer.