Figure 1.

BBM is cytotoxic to triple negative breast cancer cells. The cells were treated with applied concentrations (1.25, 2.5, 5, 10, 20, 40 or 80 µM) of BBM, cell viability was tested using MTT assay. (A) Effects of different concentrations of BBM on cell proliferation at different times. (B) The effect of BBM on cell proliferation after treatment for 72 h. The Ctrl group was the cells treated with solvent (medium containing DMSO, DMSO <0.8‰). Data are presented as the mean ± standard deviation (n=3). *P<0.05, **P<0.01, ***P<0.001 vs. Ctrl group. BBM, Berbamine; Ctrl, control.