Figure 1.

CASC9 is upregulated in BC tissues and cell lines. (A and B) RT-qPCR analysis of the relative expression levels of CASC9 in 49 pairs of BC tissues (Tumor) and matched adjacent normal tissues (Normal). The significance of statistical difference was calculated by paired Student's t-test. Error bars represent the SEM. (C) CASC9 upregulation was significantly associated with BC tumor invasion depth. The significance of statistical difference was calculated by one-way ANOVA with Bonferroni post hoc test. Error bars represent the SEM. (D) Survival curves of DFS. Patients were grouped into CASC9-low or CASC9-high groups based on CASC9 expression levels. Survival analysis was performed using log-rank test. *P<0.05, and ***P<0.001. CASC9, cancer susceptibility candidate 9; BC, bladder cancer; RT-qPCR, reverse transcription-quantitative PCR; SEM, standard error of mean; DFS, disease-free survival.