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. 2020 Oct 7;64(1):119–128. doi: 10.1007/s00125-020-05287-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Time to presence of autoantibodies by family history (mother vs father vs sibling): multiple autoantibodies defined as two or more antibodies (logrank χ² 16.2, p < 0.001) (a); GADA as first antibody (logrank χ² 4.8, p = 0.090) (b); IAA as first antibody (logrank χ² 5.5, p = 0.064) (c); IA-2A as first antibody (logrank χ² 0.55, p = 0.761) (d); ZnT8A as first antibody (logrank χ² 0.6, p = 0.73) (e); and ICA as first antibody (logrank χ² 1.2, p = 0.55) (f)