Table 2.
HR (95% CI) from univariate and multivariate Cox time to development of multiple autoantibodies model
| Variable | Univariate models | Multivariate model | ||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| Family history from mother | 0.54 (0.39, 0.75) | <0.001 | 0.70 (0.49, 1.01) | 0.055 |
| Family history from father | 0.81 (0.59, 1.11) | 0.191 | 0.93 (0.65, 1.33) | 0.682 |
| HLA risk 1a | 1.92 (1.50, 2.45) | <0.001 | 1.74 (1.33, 2.28) | <0.001 |
| Birth length | 1.06 (1.01, 1.11) | 0.012 | 1.09 (1.03, 1.16) | 0.004 |
| Height velocity (z score) | 1.03 (0.84, 1.27) | 0.758 | 1.31 (1.01, 1.70) | 0.041 |
| Weight velocity (z score) | 1.02 (0.84, 1.23) | 0.880 | ||
| Male sex | 1.27 (1.00, 1.61) | 0.054 | ||
| Birthweight | 1.08 (0.87, 1.33) | 0.494 | ||
| Gestational age, weeks | 1.05 (0.98, 1.13) | 0.168 | ||
| Region of origin | ||||
| Northern Europe | 1.11 (0.85, 1.45) | 0.449 | ||
| Central Europe | 1.10 (0.76, 1.58) | 0.614 | ||
| Vaginal delivery | 1.24 (0.97, 1.58) | 0.084 | ||
| Treatment group assignment casein hydrosylate formula | 1.13 (0.89, 1.43) | 0.314 | ||
| Exclusive breastfeeding duration | 1.05 (1.00, 1.11) | 0.071 | ||
| Birth order | 1.06 (0.95, 1.18) | 0.314 | ||
aHLA-DQB1*02/DQB1*03:02