Fig. 4.

Correlation of plasma and muscle Humanin levels and increased humanin expression within isolated mouse extensor digitorum longus (EDL) muscle during contraction. Correlation between plasma and muscle humanin levels at rest (A) and in response to exercise (B) from trained and untrained acute high-intensity exercise. Muscle humanin levels in mouse EDL (C) muscles at rest (basal) and following ex vivo contractions (contract). Curved dotted lines represent 95% confidence intervals. *P < 0.05 vs. basal for Student’s t test.